CLIC1

CLIC1, also known as Chloride Intracellular Channel 1, is a protein with several aliases like NCC27. It functions by translocating between the cytoplasm and membranes, acting as an ion channel and influencing cell volume regulation. Associated with the MAPK and PI3K - AKT signaling pathways, it modulates cellular growth and survival.
CLIC1 is linked to various diseases including cancer, where it promotes tumor cell migration and invasion. In drug development, targeting CLIC1 shows promise. Some small - molecule inhibitors are under pre - clinical evaluation to disrupt its function and potentially treat related disorders.

Popular Product:

CLIC1 Antibody (CSB-PA005545ESR1HU)

Validated Data

Western blot
All lanes: Chloride intracellular channel protein 1 antibody at 4μg/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 27 kDa
Observed band size: 27 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA005545ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA005545ESR1HU at dilution of 1:100

The following CLIC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CLIC1 Antibodies

CLIC1 Proteins

CLIC1 Antibodies

CLIC1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005545GA01HU	CLIC1 Antibody	Human,Mouse,Rat	ELISA,IHC,IF
CSB-PA005545ESR1HU	CLIC1 Antibody	Human	ELISA, WB, IHC
CSB-PA347049	CLIC1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC

CLIC1 Proteins

CLIC1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF005545HU	Recombinant Human Chloride intracellular channel protein 1 (CLIC1)	in vitro E.coli expression system
CSB-YP005545HU1 CSB-EP005545HU1 CSB-BP005545HU1 CSB-MP005545HU1 CSB-EP005545HU1-B	Recombinant Human Chloride intracellular channel protein 1 (CLIC1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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