CMKLR1 (Chemerin Chemokine-Like Receptor 1) is a G protein-coupled receptor (GPCR) composed of membrane proteins, including seven transmembrane domains. This structure allows it to bind to specific ligands, such as chemerin, and transmit signals, activating signaling pathways within cells. The binding of CMKLR1 to chemerin regulates various biological processes, including immune modulation, cell migration, inflammatory responses, and fat metabolism. It influences the activation and migration of immune cells, playing a significant role in regulating inflammatory processes and immune responses. Additionally, CMKLR1 also plays a role in fat metabolism, impacting the biological functions of adipose tissue. Research on CMKLR1 holds significant importance in the fields of immunology, inflammation, and metabolism. Understanding its role in immune cell activation, inflammation regulation, and metabolic control contributes to comprehending disease mechanisms and potentially provides new targets for disease treatment. Moreover, CMKLR1 and its ligand chemerin are considered potential targets and tools in drug development and therapy.
Recombinant Human Chemerin-like receptor 1 (CMKLR1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The following CMKLR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CMKLR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA140333 | CMKLR1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA001620 | CMKLR1 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA164672 | CMKLR1 Antibody |
Human | ELISA,IHC |
CSB-PA174496 | CMKLR1 Antibody |
Human | ELISA,IHC |
CSB-PA005614LA01HU | CMKLR1 Antibody |
Human | ELISA, IHC, IF |
CSB-PA005614LC01HU | CMKLR1 Antibody, FITC conjugated |
Human |
CMKLR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF005614MO | Recombinant Mouse Chemokine-like receptor 1 (Cmklr1) |
in vitro E.coli expression system |
CSB-YP005614MO1 CSB-EP005614MO1 CSB-BP005614MO1 CSB-MP005614MO1 CSB-EP005614MO1-B |
Recombinant Mouse Chemokine-like receptor 1 (Cmklr1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CMKLR1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF005614RA | Recombinant Rat Chemokine-like receptor 1 (Cmklr1) |
in vitro E.coli expression system |
CSB-YP005614RA1 CSB-EP005614RA1 CSB-BP005614RA1 CSB-MP005614RA1 CSB-EP005614RA1-B |
Recombinant Rat Chemokine-like receptor 1 (Cmklr1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CMKLR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF005614HU | Recombinant Human Chemerin-like receptor 1 (CMKLR1) |
in vitro E.coli expression system |
CSB-YP005614HU1 CSB-BP005614HU1 CSB-MP005614HU1 CSB-EP005614HU1-B |
Recombinant Human Chemokine-like receptor 1 (CMKLR1), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP005614HU | Recombinant Human Chemokine-like receptor 1 (CMKLR1)-VLPs |
Mammalian cell |
CSB-EP005614HU1 | Recombinant Human Chemokine-like receptor 1 (CMKLR1), partial |
E.coli |
CSB-CF005614HUd7 | Recombinant Human Chemerin-like receptor 1 (CMKLR1) |
in vitro E.coli expression system |