CXCR6

CXCR6, also known as C-X-C chemokine receptor type 6, is a G-protein coupled receptor. It is also commonly referred to as STRL33 or Bonzo. This protein binds specifically to the chemokine CXCL16. Through this interaction, it activates intracellular signaling pathways, mainly the Gαi pathway, leading to cell migration and activation.
CXCR6 has been associated with various diseases, including autoimmune diseases and certain types of cancer. In autoimmune diseases, it contributes to the recruitment of immune cells to inflamed tissues. In cancer, it may promote tumor metastasis. Currently, there are ongoing efforts in drug development to target CXCR6, aiming to block its function and potentially treat these related diseases.

Validated Data

CSB-MP006256HU is detected by Mouse anti-6*His monoclonal antibody.

The purity of VLPs was greater than 90% as determined by SEC-HPLC

CXCR6 Antibody (CSB-PA005634)

Validated Data

Western Blot analysis of HeLa cells using Bonzo Polyclonal Antibody.

The following CXCR6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CXCR6 Antibodies

CXCR6 Proteins

CXCR6 Antibodies

CXCR6 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005634	CXCR6 Antibody	Human	WB, ELISA
CSB-PA224134	CXCR6 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA188638	CXCR6 Antibody	Human,Mouse	ELISA,WB,IHC

CXCR6 Proteins

CXCR6 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-CF866150EQV	Recombinant Pan troglodytes C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP866150EQV1 CSB-EP866150EQV1 CSB-BP866150EQV1 CSB-MP866150EQV1 CSB-EP866150EQV1-B	Recombinant Pan troglodytes C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCR6 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF006256HU	Recombinant Human C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP006256HU1 CSB-EP006256HU1 CSB-BP006256HU1 CSB-MP006256HU1 CSB-EP006256HU1-B	Recombinant Human C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP006256HU	Recombinant Human C-X-C chemokine receptor type 6 (CXCR6)-VLPs	Mammalian cell

CXCR6 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Code	Product Name	Source
CSB-CF006256DSU	Recombinant Chlorocebus aethiops C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP006256DSU1 CSB-EP006256DSU1 CSB-BP006256DSU1 CSB-MP006256DSU1 CSB-EP006256DSU1-B	Recombinant Chlorocebus aethiops C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCR6 Proteins for Macaca nemestrina (Pig-tailed macaque)

Code	Product Name	Source
CSB-CF006256MOX	Recombinant Macaca nemestrina C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP006256MOX1 CSB-EP006256MOX1 CSB-BP006256MOX1 CSB-MP006256MOX1 CSB-EP006256MOX1-B	Recombinant Macaca nemestrina C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCR6 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-CF861038MOV	Recombinant Macaca fascicularis C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP861038MOV1 CSB-EP861038MOV1 CSB-BP861038MOV1 CSB-MP861038MOV1 CSB-EP861038MOV1-B	Recombinant Macaca fascicularis C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCR6 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Code	Product Name	Source
CSB-CF878786DRI	Recombinant Cercocebus atys C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP878786DRI1 CSB-EP878786DRI1 CSB-BP878786DRI1 CSB-MP878786DRI1 CSB-EP878786DRI1-B	Recombinant Cercocebus atys C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCR6 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-CF893172MOW	Recombinant Macaca mulatta C-X-C chemokine receptor type 6 (CXCR6)	in vitro E.coli expression system
CSB-YP893172MOW1 CSB-EP893172MOW1 CSB-BP893172MOW1 CSB-MP893172MOW1 CSB-EP893172MOW1-B	Recombinant Macaca mulatta C-X-C chemokine receptor type 6 (CXCR6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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CXCR6

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