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Cytoplasmic FMR1-interacting protein 1 is a protein in humans that is encoded by CYFIP1 gene. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.
The following CYFIP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CYFIP1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA856207XA01DIL | cyfip1 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
CYFIP1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA748722LA01HU | CYFIP1 Antibody |
Human | ELISA, IF |
CYFIP1 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP006374BO CSB-EP006374BO CSB-BP006374BO CSB-MP006374BO CSB-EP006374BO-B |
Recombinant Bovine Cytoplasmic FMR1-interacting protein 1 (CYFIP1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CYFIP1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP742490MO CSB-EP742490MO CSB-BP742490MO CSB-MP742490MO CSB-EP742490MO-B |
Recombinant Mouse Cytoplasmic FMR1-interacting protein 1 (Cyfip1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CYFIP1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP748722HU CSB-EP748722HU CSB-BP748722HU CSB-MP748722HU CSB-EP748722HU-B |
Recombinant Human Cytoplasmic FMR1-interacting protein 1 (CYFIP1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CYFIP1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP856207DIL CSB-EP856207DIL CSB-BP856207DIL CSB-MP856207DIL CSB-EP856207DIL-B |
Recombinant Danio rerio Cytoplasmic FMR1-interacting protein 1 homolog (cyfip1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
