DSC2

DSC2 encodes Desmocollin - 2, also commonly known as DSCII. It is a key component of desmosomes, which are essential for cell - cell adhesion in tissues. Mechanistically, Desmocollin - 2 interacts with other desmosomal proteins to provide mechanical stability to cells. It is involved in the Wnt signaling pathway, regulating cell proliferation and differentiation.
Aberrant expression of DSC2 is linked to various diseases, including arrhythmogenic right ventricular cardiomyopathy. In drug development, current research is focused on targeting the protein - protein interactions of DSC2 to develop therapies for related heart diseases. However, more in - depth studies are needed for successful clinical translation.