ERCC1 Research Reagents

DNA excision repair protein ERCC-1is a protein in humans that is encoded by ERCC1 gene. ogether with ERCC4, ERCC1 forms the ERCC1-XPF enzyme complex that participates in DNA repair and DNA recombination. Many aspects of these two gene products are described together here because they are partners during DNA repair. The ERCC1-XPF nuclease is an essential activity in the pathway of DNA nucleotide excision repair (NER). The ERCC1-XPF nuclease also functions in pathways to repair double-strand breaks in DNA, and in the repair of “crosslink” damage that harmfully links the two DNA strands. Cells with disabling mutations in ERCC1 are more sensitive than normal to particular DNA damaging agents, including ultraviolet (UV) radiation and to chemicals that cause crosslinking between DNA strands.

The following ERCC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ERCC1 Antibodies

ERCC1 Antibodies for Homo sapiens (Human)

ERCC1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

ERCC1 Proteins

ERCC1 Proteins for Mus musculus (Mouse)

ERCC1 Proteins for Homo sapiens (Human)

ERCC1 Proteins for Bos taurus (Bovine)

ERCC1 Proteins for Dictyostelium discoideum (Slime mold)

ERCC1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

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