EXO1

Exonuclease 1 is a protein in humans that is encoded by EXO1 gene. 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

EXO1 Antibodies

EXO1 Antibodies for Homo sapiens (Human)

EXO1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

EXO1 Antibodies for Oryza sativa subsp. japonica (Rice)

EXO1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

EXO1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

EXO1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

EXO1 Proteins

EXO1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

EXO1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

EXO1 Proteins for Dictyostelium discoideum (Slime mold)

EXO1 Proteins for Oryza sativa subsp. japonica (Rice)

EXO1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

EXO1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

EXO1 Proteins for Mus musculus (Mouse)

EXO1 Proteins for Homo sapiens (Human)

EXO1 Proteins for Xenopus laevis (African clawed frog)

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