FLRT3

FLRT3, also known as Fibronectin Leucine - Rich Transmembrane Protein 3, is a protein encoded by the FLRT3 gene. It has no well - known aliases. FLRT3 plays a crucial role in cell adhesion and migration. It interacts with other membrane proteins to regulate the cytoskeleton, thereby influencing cell movement. It is involved in the planar cell polarity (PCP) signaling pathway.
Abnormal expression of FLRT3 is associated with several diseases, such as neuronal migration disorders due to its importance in neurodevelopment. In drug development, research is in the early stages. Scientists are exploring drugs that can modulate its function to treat related diseases, aiming to correct the abnormal cell behaviors caused by FLRT3 dysregulation.