FZD6 Research Reagents

Frizzled-6 is a protein in humans that is encoded by FZD6 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.

The following FZD6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FZD6 Antibodies

FZD6 Antibodies for Homo sapiens (Human)

FZD6 Proteins

FZD6 Proteins for Gallus gallus (Chicken)

FZD6 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

FZD6 Proteins for Homo sapiens (Human)

FZD6 Proteins for Mus musculus (Mouse)

FZD6 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

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