Frizzled-6 is a protein in humans that is encoded by FZD6 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
The following FZD6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FZD6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA060237 | FZD6 Antibody | Human | WB, IF, ELISA |
CSB-PA060238 | FZD6 Antibody | Human | WB, IHC, IF, ELISA |
CSB-PA032335 | FZD6 Antibody | Human,Mouse | ELISA,IHC |
FZD6 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-CF865511CH | Recombinant Chicken Frizzled-6 (FZD6) | in vitro E.coli expression system |
CSB-YP865511CH1 CSB-EP865511CH1 CSB-BP865511CH1 CSB-MP865511CH1 CSB-EP865511CH1-B |
Recombinant Chicken Frizzled-6 (FZD6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD6 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-CF716182PYX | Recombinant Pongo abelii Frizzled-6 (FZD6) | in vitro E.coli expression system |
CSB-YP716182PYX1 CSB-EP716182PYX1 CSB-BP716182PYX1 CSB-MP716182PYX1 CSB-EP716182PYX1-B |
Recombinant Pongo abelii Frizzled-6 (FZD6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF009109HU | Recombinant Human Frizzled-6 (FZD6) | in vitro E.coli expression system |
CSB-YP009109HU1 CSB-EP009109HU1 CSB-BP009109HU1 CSB-MP009109HU1 CSB-EP009109HU1-B |
Recombinant Human Frizzled-6 (FZD6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD6 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF717196MO | Recombinant Mouse Frizzled-6 (Fzd6) | in vitro E.coli expression system |
CSB-YP717196MO1 CSB-EP717196MO1 CSB-BP717196MO1 CSB-MP717196MO1 CSB-EP717196MO1-B |
Recombinant Mouse Frizzled-6 (Fzd6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD6 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-CF837830DO | Recombinant Dog Frizzled-6 (FZD6) | in vitro E.coli expression system |
CSB-YP837830DO1 CSB-EP837830DO1 CSB-BP837830DO1 CSB-MP837830DO1 CSB-EP837830DO1-B |
Recombinant Dog Frizzled-6 (FZD6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |