The gap junction protein 26 (Cx26), encoded by the GJB2 gene, plays a crucial role in the human body. Structurally, Cx26 is a transmembrane protein containing 226 amino acids and is located on the cell membrane. Functionally, it participates in intercellular signal transmission, maintains normal hearing function, and is also crucial for breastfeeding and inner ear balance. However, the specific mechanism of action of the GJB2 gene in signaling pathways remains to be further investigated. Additionally, variations in the GJB2 gene are closely associated with the degree of hearing loss, with different variant types potentially leading to varying degrees of hearing impairment. In summary, the GJB2 gene and its encoded protein play significant roles in maintaining hearing and intercellular signal transmission. Research on their structure and function is crucial for understanding the pathogenesis of diseases such as hearing loss and finding effective treatments.
The following GJB2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GJB2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009452GA01HU | GJB2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA001757 | GJB2 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA549840 | GJB2 Antibody |
Human,Rat | ELISA,IHC |
CSB-PA009452LA01HU | GJB2 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA009452LB01HU | GJB2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA009452LC01HU | GJB2 Antibody, FITC conjugated |
Human | |
CSB-PA009452LD01HU | GJB2 Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA009452MA1HU | GJB2 Recombinant Monoclonal Antibody |
Human | ELISA, IHC, FC |
GJB2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF009452HU | Recombinant Human Gap junction beta-2 protein (GJB2) |
in vitro E.coli expression system |
CSB-YP009452HU1 CSB-EP009452HU1 CSB-BP009452HU1 CSB-MP009452HU1 CSB-EP009452HU1-B |
Recombinant Human Gap junction beta-2 protein (GJB2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |