HSPA1B

The HSPA1B gene encodes the heat shock 70 kDa protein 1B, also commonly known as Hsp70-2. This protein belongs to the heat - shock protein 70 (Hsp70) family. It functions as a molecular chaperone, assisting in protein folding, preventing protein aggregation, and helping damaged proteins to be refolded or degraded. It is involved in the PI3K - Akt and MAPK signaling pathways.
HSPA1B is associated with several diseases, including neurodegenerative disorders and certain cancers. In drug development, some small - molecule inhibitors targeting HSPA1B are being investigated. These inhibitors aim to disrupt its function in cancer cells, potentially providing new therapeutic options for cancer treatment.

Popular Product:

HSPA1B Antibody (CSB-PA28047A0Rb)

Validated Data

Western Blot
Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, PC3 whole cell lysate, K562 whole cell lysate
All lanes: HSPA1B antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71 kDa
Observed band size: 71 kDa

Immunofluorescence staining of PC3 cells with CSB-PA28047A0Rb at 1:106, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human Heat Shock Protein 70,HSP-70 ELISA Kit (CSB-E08297h)

Validated Data

Code: CSB-E08297h

Size: 96T,5×96T,10×96T

Sensitivity: 0.39 ng/mL

Detection Range: 1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following HSPA1B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HSPA1B Antibodies

HSPA1B ELISA Kits

HSPA1B Antibodies

HSPA1B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA28047A0Rb	HSPA1B Antibody	Human	ELISA, WB, IF
CSB-PA28047B0Rb	HSPA1B Antibody, HRP conjugated	Human	ELISA
CSB-PA28047C0Rb	HSPA1B Antibody, FITC conjugated	Human
CSB-PA28047D0Rb	HSPA1B Antibody, Biotin conjugated	Human	ELISA

HSPA1B ELISA Kit

HSPA1B ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08297h	Human Heat Shock Protein 70,HSP-70 ELISA Kit	serum, plasma, tissue homogenates	0.39 ng/mL

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