ID2 Research Reagents

DNA-binding protein inhibitor ID-2 is a protein in humans that is encoded by ID2 gene. Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock

The following ID2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ID2 Antibodies

ID2 Antibodies for Homo sapiens (Human)

ID2 Proteins

ID2 Proteins for Mus musculus (Mouse)

ID2 Proteins for Rattus norvegicus (Rat)

ID2 Proteins for Sus scrofa (Pig)

ID2 Proteins for Bos taurus (Bovine)

ID2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

ID2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

ID2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

ID2 Proteins for Homo sapiens (Human)

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