IDE is a protein in humans that is encoded by IDE gene. Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin. Contributes to the regulation of peptide hormone signaling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP (By similarity). Plays a role in the degradation and clearance of APP-derived amyloidogenic peptides that are secreted by neurons and microglia (Probable). Involved in antigen processing. Produces both the N terminus and the C terminus of MAGEA3-derived antigenic peptide (EVDPIGHLY) that is presented to cytotoxic T lymphocytes by MHC class I.
The following IDE reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IDE Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010988GA01HU | IDE Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-MA000241 | IDE Monoclonal Antibody |
Human | ELISA,WB |
CSB-PA194156 | IDE Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA869336 | IDE Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA010988LA01HU | IDE Antibody |
Human | ELISA, IHC, IF |
CSB-PA010988LB01HU | IDE Antibody, HRP conjugated |
Human | ELISA |
CSB-PA010988LD01HU | IDE Antibody, Biotin conjugated |
Human | ELISA |
IDE Antibodies for Drosophila melanogaster (Fruit fly)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010988XA01DLU | Ide Antibody |
Drosophila melanogaster (Fruit fly) | ELISA, WB (ensure identification of antigen) |
IDE Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010988HU CSB-EP010988HU CSB-BP010988HU CSB-MP010988HU CSB-EP010988HU-B |
Recombinant Human Insulin-degrading enzyme (IDE), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IDE Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP010988RA CSB-EP010988RA CSB-BP010988RA CSB-MP010988RA CSB-EP010988RA-B |
Recombinant Rat Insulin-degrading enzyme (Ide), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IDE Proteins for Drosophila melanogaster (Fruit fly)
Code | Product Name | Source |
---|---|---|
CSB-YP010988DLU CSB-EP010988DLU CSB-BP010988DLU CSB-MP010988DLU CSB-EP010988DLU-B |
Recombinant Drosophila melanogaster Insulin-degrading enzyme (Ide), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IDE Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP010988MO CSB-EP010988MO CSB-BP010988MO CSB-MP010988MO CSB-EP010988MO-B |
Recombinant Mouse Insulin-degrading enzyme (Ide), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IDE Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP010988BO CSB-EP010988BO CSB-BP010988BO CSB-MP010988BO CSB-EP010988BO-B |
Recombinant Bovine Insulin-degrading enzyme (IDE), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |