IGSF1

IGSF1 encodes the Immunoglobulin Superfamily Member 1 protein, also commonly known as IGSF-1. This protein is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is mainly involved in cell - cell adhesion and signaling. It participates in multiple signaling pathways related to cell growth, differentiation, and immune responses.
Mutations in IGSF1 are associated with central hypothyroidism and variable degrees of gonadotropin deficiency. Regarding drug development, current research is focused on understanding its precise role in these pathways. Preliminary studies aim to develop targeted therapies to modulate IGSF1 - related signaling for treating the associated diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following IGSF1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

IGSF1 Proteins

IGSF1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP854051HU CSB-EP854051HU CSB-BP854051HU CSB-MP854051HU CSB-EP854051HU-B	Recombinant Human Immunoglobulin superfamily member 1 (IGSF1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP854051HU(A4)	Recombinant Human Immunoglobulin superfamily member 1 (IGSF1)-VLPs	Mammalian cell

IGSF1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF854051HU(A4)	Recombinant Human Immunoglobulin superfamily member 1 (IGSF1)	in vitro E.coli expression system

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Popular Pathways

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Hippo signaling pathway

TGF-beta signaling pathway

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IGSF1

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