IL6RA, the alpha subunit of the interleukin-6 receptor, is a type I transmembrane glycoprotein that is secreted by various cells, including those of the immune system, epithelia, and adipose tissue. By binding to IL-6 and forming a complex with the membrane protein gp130, IL6RA triggers the activation of signaling pathways such as JAK/STAT, MAPK, and Akt, which are crucial for regulating cell growth, differentiation, immune responses, acute phase reactions, and hematopoiesis. Dysfunction of IL6RA is implicated in the development of numerous diseases, including multiple myeloma, autoimmune disorders, and prostate cancer.
Recombinant Human Interleukin-6 receptor subunit alpha (IL6R), partial (CSB-YP011665HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Interleukin 6 receptor(IL-6R)ELISA Kit (CSB-E16524h)
Validated Data
Code: CSB-E16524h
Size: 96T,5×96T,10×96T
Sensitivity: 0.039 ng/mL
Detection Range: 0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following IL6RA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IL6RA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006108 | IL6R Antibody | Human | WB, ELISA |
IL6RA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP011665HU CSB-BP011665HU CSB-MP011665HU CSB-EP011665HU-B |
Recombinant Human Interleukin-6 receptor subunit alpha (IL6R), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL6RA ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E16524h | Human Interleukin 6 receptor(IL-6R)ELISA Kit | serum, plasma, tissue homogenates | 0.039 ng/mL |