ITGA4

Integrin alpha-4 is a protein in humans that is encoded by ITGA4 gene. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

ITGA4 Antibodies

ITGA4 Antibodies for Homo sapiens (Human)

ITGA4 Proteins

ITGA4 Proteins for Homo sapiens (Human)

ITGA4 Proteins for Xenopus laevis (African clawed frog)

ITGA4 ELISA Kit

ITGA4 ELISA Kit for Homo sapiens (Human)

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