Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression (By similarity).
The following KDM6A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KDM6A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025774LB01HU | KDM6A Antibody, HRP conjugated |
Human | ELISA |
CSB-PA025774LC01HU | KDM6A Antibody, FITC conjugated |
Human | |
CSB-PA025774LD01HU | KDM6A Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA025774LA01HU | KDM6A Antibody |
Human | ELISA, IHC |
KDM6A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP025774HU CSB-BP025774HU CSB-MP025774HU CSB-EP025774HU-B |
Recombinant Human Lysine-specific demethylase 6A (KDM6A), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KDM6A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP025774MO CSB-EP025774MO CSB-BP025774MO CSB-MP025774MO CSB-EP025774MO-B |
Recombinant Mouse Lysine-specific demethylase 6A (Kdm6a), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |