Linker for activation of T-cells family member 1 is a protein in humans that is encoded by LAT gene. Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
The following LAT reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
LAT Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA012767GA01HU | LAT Antibody |
Human | ELISA,WB |
CSB-PA012767ESR2HU | LAT Antibody |
Human | ELISA |
CSB-PA153832 | LAT (Ab-255) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA003139 | LAT Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA003140 | LAT Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA008846 | Phospho-LAT (Y200) Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA008847 | Phospho-LAT (Y191) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008848 | LAT Antibody |
Human | WB, ELISA |
CSB-RA012767A191phHU | Phospho-LAT (Y191) Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC, IF, IP |
LAT Antibodies for Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA843707XA01FSR | lat Antibody |
Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602) | ELISA, WB (ensure identification of antigen) |
LAT Proteins for Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Code | Product Name | Source |
---|---|---|
CSB-YP350562MVH CSB-EP350562MVH CSB-BP350562MVH CSB-MP350562MVH CSB-EP350562MVH-B |
Recombinant Probable L-lysine-epsilon aminotransferase (lat) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LAT Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF012767RA | Recombinant Rat Linker for activation of T-cells family member 1 (Lat) |
in vitro E.coli expression system |
CSB-YP012767RA1 CSB-EP012767RA1 CSB-BP012767RA1 CSB-MP012767RA1 CSB-EP012767RA1-B |
Recombinant Rat Linker for activation of T-cells family member 1 (Lat), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LAT Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF012767MO | Recombinant Mouse Linker for activation of T-cells family member 1 (Lat) |
in vitro E.coli expression system |
CSB-YP012767MO1 CSB-EP012767MO1 CSB-BP012767MO1 CSB-MP012767MO1 CSB-EP012767MO1-B |
Recombinant Mouse Linker for activation of T-cells family member 1 (Lat), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LAT Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF012767HU | Recombinant Human Linker for activation of T-cells family member 1 (LAT) |
in vitro E.coli expression system |
CSB-YP012767HU1 CSB-EP012767HU1 CSB-BP012767HU1 CSB-MP012767HU1 CSB-EP012767HU1-B |
Recombinant Human Linker for activation of T-cells family member 1 (LAT), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |