LAT Research Reagents

Linker for activation of T-cells family member 1 is a protein in humans that is encoded by LAT gene. Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

The following LAT reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

LAT Antibodies

LAT Antibodies for Homo sapiens (Human)

LAT Antibodies for Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)

LAT Proteins

LAT Proteins for Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

LAT Proteins for Rattus norvegicus (Rat)

LAT Proteins for Mus musculus (Mouse)

LAT Proteins for Homo sapiens (Human)


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