LRP4, a member of the low density lipoprotein receptor (LDLR) family and coded by a human gene, is intricately involved in the regulation of MuSK activation, acetylcholine receptor clustering, and the formation of neuromuscular junctions (NMJ). This protein is pivotal for the proper presynaptic development and the upkeep of synaptic terminals in the neuromuscular system. Its dysfunction is implicated in the pathogenesis of myasthenia gravis, offering novel insights into the study and treatment of this disease.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
LRP4 Antibody (CSB-PA013099ESR1HU)
Validated Data
Western blot
All lanes: LRP4 antibody at 1.39µg/ml + PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 213 kDa
Observed band size: 213 kDa
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA013099ESR1HU at dilution of 1:100
The following LRP4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
LRP4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013099ESR1HU | LRP4 Antibody | Human | ELISA, WB, IHC |
CSB-PA013099ESR2HU | LRP4 Antibody | Human | ELISA, IHC |
LRP4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP013099HU | Recombinant Human Low-density lipoprotein receptor-related protein 4 (LRP4), partial | E.coli |
CSB-MP013099HU CSB-EP013099HU-B |
Recombinant Human Low-density lipoprotein receptor-related protein 4 (LRP4), partial | Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP013099HU | Recombinant Human Low-density lipoprotein receptor-related protein 4 (LRP4), partial,Yeast | Yeast |
LRP4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E17518h | Human low-density lipoprotein-receptor-related protein 4(LRP-4)ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/mL |