MAGEA4, a member of the MAGE family located on chromosome X, is a protein whose expression is typically associated with cancer cells, contrasting with its low or absent presence in normal tissues, particularly in immune-privileged regions like the testes. This protein's role in tumors may involve the suppression of apoptosis and the stimulation of cancer growth. MAGEA4 also serves as a target for immunotherapies, harnessing the immune system to target cancer cells. Its expression across various cancers, such as lung, ovarian, and melanoma, correlates closely with tumor aggressiveness and patient outcomes, making MAGEA4 a significant biomarker for detection and a potential therapeutic target.
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) (CSB-MP013330HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 μg/ml can bind anti-MAGEA4 recombinant antibody, the EC50 is 30.33-43.10 ng/mL.
MAGEA4 Antibody (CSB-PA013330LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA013330LA01HU at dilution of 1:100
The following MAGEA4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MAGEA4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013330GA01HU | MAGEA4 Antibody | Human | ELISA,IHC |
CSB-PA059198 | MAGEA4 Antibody | Human | ELISA,IHC |
CSB-PA179901 | MAGEA4 Antibody | Human | ELISA,IHC |
CSB-PA013330LA01HU | MAGEA4 Antibody | Human | ELISA, IHC |
CSB-PA013330LD01HU | MAGEA4 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA013330LC01HU | MAGEA4 Antibody, FITC conjugated | Human | |
CSB-PA013330LB01HU | MAGEA4 Antibody, HRP conjugated | Human | ELISA |
CSB-MA013330A0m | MAGEA4 Monoclonal Antibody | Human | ELISA, IHC, FC |
MAGEA4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP013330HU CSB-EP013330HU CSB-BP013330HU CSB-MP013330HU CSB-EP013330HU-B |
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP013330HU(M) | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |
CSB-MP013330HU | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) | Mammalian cell |
CSB-EP013330HUb0 | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |