MAPK14 Research Reagents

Mitogen-activated protein kinase 14 is a protein in humans that is encoded by MAPK14 gene. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets. RPS6KA5/MSK1 and RPS6KA4/MSK2 can directly phosphorylate and activate transcription factors such as CREB1, ATF1, the NF-kappa-B isoform RELA/NFKB3, STAT1 and STAT3, but can also phosphorylate histone H3 and the nucleosomal protein HMGN1.

The following MAPK14 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MAPK14 Antibodies

MAPK14 Antibodies for Homo sapiens (Human)

MAPK14 Proteins

MAPK14 Proteins for Rattus norvegicus (Rat)

MAPK14 Proteins for Mus musculus (Mouse)

MAPK14 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

MAPK14 Proteins for Xenopus laevis (African clawed frog)

MAPK14 Proteins for Pan troglodytes (Chimpanzee)

MAPK14 Proteins for Homo sapiens (Human)

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