MARK1 is a protein in humans that is encoded by MARK1 gene. Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
The following MARK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MARK1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013496GA01HU | MARK1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA219426 | MARK1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA907425 | MARK1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA473505 | MARK1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA850358 | MARK1 Antibody | Human | ELISA,WB,IHC |
CSB-PA259165 | MARK1 Antibody | Human | ELISA,IHC |
CSB-PA873719DSR1HU | MARK1 Antibody | Human, Rat | ELISA, WB, IHC |
MARK1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP013496RA CSB-EP013496RA CSB-BP013496RA CSB-MP013496RA CSB-EP013496RA-B |
Recombinant Rat Serine/threonine-protein kinase MARK1 (Mark1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MARK1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP848705MO CSB-EP848705MO CSB-BP848705MO CSB-MP848705MO CSB-EP848705MO-B |
Recombinant Mouse Serine/threonine-protein kinase MARK1 (Mark1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MARK1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP873719HU CSB-EP873719HU CSB-BP873719HU CSB-MP873719HU CSB-EP873719HU-B |
Recombinant Human Serine/threonine-protein kinase MARK1 (MARK1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |