MECP2, an essential gene located on chromosome Xq28, encodes the MeCP2 protein that possesses methyl-binding, nuclear localization, and transcriptional repression domains. MeCP2 primarily regulates the transcription of other genes by recognizing and binding to methylated sites on DNA, acting as both a transcriptional repressor and activator. It is abundantly expressed in the nervous system and plays a crucial role in the development and maturation of the central nervous system, as well as in learning and memory functions. However, mutations in MECP2 are closely associated with neurodevelopmental disorders such as Rett syndrome. Although we know that MeCP2 is involved in complex signaling networks, the specific signaling pathways and interaction mechanisms with other molecules remain to be further elucidated. Therefore, a thorough investigation of the structure, function, and signaling pathways of MECP2 is crucial for understanding the development and function of the nervous system, as well as the pathogenesis of genetic diseases.
Recombinant Human Methyl-CpG-binding protein 2 (MECP2)
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following MECP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MECP2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013638GA01HU | MECP2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA013638ESR2HU | MECP2 Antibody |
Human | ELISA, IHC |
CSB-PA912786 | MECP2 Antibody |
Human | ELISA,WB |
CSB-PA000357 | MECP2 Antibody |
Human | WB |
CSB-PA440474 | MECP2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
MECP2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP013638HU CSB-EP013638HU CSB-BP013638HU CSB-MP013638HU CSB-EP013638HU-B |
Recombinant Human Methyl-CpG-binding protein 2 (MECP2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |