METTL14

METTL14, or KIAA1539, is an RNA methylation enzyme encoded by the METTL14 gene, participating in the m6A modification of RNA. It adds a methyl group to RNA adenosines to form m6A, a modification that regulates mRNA stability, splicing, transport, and translation. METTL14 dysfunction is associated with diseases, especially cancers, where its misexpression or altered activity can drive tumorigenesis and metastasis. Additionally, METTL14 is involved in nervous system development and cognitive function, with mutations linked to neurodevelopmental disorders.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

METTL14 Antibody (CSB-PA884519LA01HU)

Validated Data

Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate
All lanes: METTL14 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53 kDa
Observed band size: 53 kDa

The following METTL14 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

METTL14 Antibodies

METTL14 Proteins

METTL14 Antibodies

METTL14 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA884519LA01HU	METTL14 Antibody	Human	ELISA, WB
CSB-PA884519LB01HU	METTL14 Antibody, HRP conjugated	Human	ELISA
CSB-PA884519LC01HU	METTL14 Antibody, FITC conjugated	Human
CSB-PA884519LD01HU	METTL14 Antibody, Biotin conjugated	Human	ELISA

METTL14 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA757538XA01DIL	mettl14 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

METTL14 Proteins

METTL14 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP013729BO CSB-EP013729BO CSB-BP013729BO CSB-MP013729BO CSB-EP013729BO-B	Recombinant Bovine N6-adenosine-methyltransferase non-catalytic subunit (METTL14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP667575MO CSB-EP667575MO CSB-BP667575MO CSB-MP667575MO CSB-EP667575MO-B	Recombinant Mouse Methyltransferase-like protein 14 (Mettl14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP724142XBF CSB-EP724142XBF CSB-BP724142XBF CSB-MP724142XBF CSB-EP724142XBF-B	Recombinant Xenopus tropicalis Methyltransferase-like protein 14 (mettl14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP726511CH CSB-EP726511CH CSB-BP726511CH CSB-MP726511CH CSB-EP726511CH-B	Recombinant Chicken Methyltransferase-like protein 14 (METTL14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP732620PYX CSB-EP732620PYX CSB-BP732620PYX CSB-MP732620PYX CSB-EP732620PYX-B	Recombinant Pongo abelii Methyltransferase-like protein 14 (METTL14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP747347XBE CSB-EP747347XBE CSB-BP747347XBE CSB-MP747347XBE CSB-EP747347XBE-B	Recombinant Xenopus laevis Methyltransferase-like protein 14 (mettl14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP757538DIL CSB-EP757538DIL CSB-BP757538DIL CSB-MP757538DIL CSB-EP757538DIL-B	Recombinant Danio rerio Methyltransferase-like protein 14 (mettl14)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

METTL14 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP884519HU CSB-BP884519HU CSB-MP884519HU CSB-EP884519HU-B	Recombinant Human N6-adenosine-methyltransferase non-catalytic subunit (METTL14)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP884519HU	Recombinant Human N6-adenosine-methyltransferase non-catalytic subunit (METTL14)	E.coli

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METTL14

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