MTCH2 encodes the mitochondrial carrier homolog 2 protein, also commonly known as MINOS1-interacting protein. This protein is a key component of the mitochondrial outer membrane. It functions in controlling mitochondrial dynamics and maintaining mitochondrial integrity by interacting with other proteins. It is involved in the mitochondrial fission and fusion signaling pathway.
Abnormalities in MTCH2 have been linked to metabolic disorders such as obesity and type - 2 diabetes. In the field of drug research, some small - molecule compounds are being explored for their potential to regulate MTCH2 activity, aiming to develop new therapies for related metabolic diseases. However, more research is needed to fully understand its function and develop effective drugs.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA083456(MTCH2 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Human testis tissue, K562 cells, PC3 cells, human liver cancer tissue, hela cells, Primary antibody: CSB-PA083456(MTCH2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
The following MTCH2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MTCH2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015133GA01HU | MTCH2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA083456 | MTCH2 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA897586LA01HU | MTCH2 Antibody | Human | ELISA, IHC |
CSB-PA897586LB01HU | MTCH2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA897586LC01HU | MTCH2 Antibody, FITC conjugated | Human | |
CSB-PA897586LD01HU | MTCH2 Antibody, Biotin conjugated | Human | ELISA |
MTCH2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF897586HU | Recombinant Human Mitochondrial carrier homolog 2 (MTCH2) | in vitro E.coli expression system |
CSB-YP897586HU1 CSB-EP897586HU1 CSB-BP897586HU1 CSB-MP897586HU1 CSB-EP897586HU1-B |
Recombinant Human Mitochondrial carrier homolog 2 (MTCH2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |