NADK, or nicotinamide adenine dinucleotide kinase, is also known as NAD kinase, NAD+ kinase, and so on. NADK is a widespread enzyme in many organisms, encoded by its own gene in human cells.NADK's main role is to catalyze the phosphorylation of NAD+ (nicotinamide adenine dinucleotide) to NADP+ (phosphonic nicotinamide adenine dinucleotide), a reaction that is reversible, but is usually dominated by the production of NADP+ in cells.NADK plays an important role in cellular energy metabolism and redox balance, especially in the maintenance of NADPH levels.NADK plays an important role in cellular energy metabolism and redox balance, especially in the maintenance of NADPH levels. NADK plays an important role in cellular energy metabolism and redox homeostasis, especially in the maintenance of NADPH levels.
NADK has a wide range of biological significance and is involved in a variety of intracellular signaling pathways and metabolic processes.NADPH, as a strong reductant, is essential for the maintenance of the intracellular redox state, and is involved in a variety of biochemical reactions such as the cellular antioxidant defenses, fatty acid synthesis, cholesterol synthesis, and so on.NADK's activity is regulated by a variety of factors, including intracellular calcium ion levels, pH, and energy status. In addition, the abnormal function of NADK has been associated with certain diseases, for example, in some cancers, the expression level of NADK may be correlated with the metabolic properties and chemosensitivity of tumor cells. Thus, NADK is a potential target in cell metabolism and disease therapy.
NADK Antibody (CSB-PA015409LA01HU)
Validated Data
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate
All lanes: NADK antibody at 1.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50, 64, 47 kDa
Observed band size: 47 kDa
The following NADK reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NADK Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015409GA01HU | NADK Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA015409LA01HU | NADK Antibody | Human | ELISA, WB |
CSB-PA015409LC01HU | NADK Antibody, FITC conjugated | Human | |
CSB-PA015409LD01HU | NADK Antibody, Biotin conjugated | Human | ELISA |
NADK Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP015409HU CSB-EP015409HU CSB-BP015409HU CSB-MP015409HU CSB-EP015409HU-B |
Recombinant Human NAD kinase (NADK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |