Neurogenic locus notch homolog protein 4 is a protein in humans that is encoded by NOTCH4 gene. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
The following NOTCH4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NOTCH4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020146 | Cleaved-NOTCH4 (V1432) Antibody |
Human,Monkey | WB, ELISA |
CSB-PA446675 | NOTCH4 Antibody |
Human | ELISA,WB,IHC |
CSB-PA995547 | NOTCH4 Antibody |
Human | ELISA,IHC |
NOTCH4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP015953MO CSB-EP015953MO CSB-BP015953MO CSB-MP015953MO CSB-EP015953MO-B |
Recombinant Mouse Neurogenic locus notch homolog protein 4 (Notch4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOTCH4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP860341HU CSB-EP860341HU CSB-BP860341HU CSB-MP860341HU CSB-EP860341HU-B |
Recombinant Human Neurogenic locus notch homolog protein 4 (NOTCH4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |