NTN4, also known as Netrin-4, is a protein with several common aliases. This protein plays a crucial role in axon guidance and neural development. It binds to specific receptors, influencing cell adhesion and migration. In terms of signaling pathways, it is involved in the UNC5 and DCC receptor - mediated pathways. NTN4 dysregulation has been associated with neurological disorders and some types of cancers.
Regarding drug development, research is underway to target the NTN4 - related pathways. Scientists aim to develop drugs that can modulate its function to treat associated diseases. Although there are currently no approved drugs, pre - clinical studies show potential in regulating NTN4 for therapeutic benefits.
Recombinant Human Netrin-4 (NTN4), partial (CSB-EP881014HU1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The following NTN4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NTN4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
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CSB-YP881014HU CSB-EP881014HU CSB-BP881014HU CSB-MP881014HU CSB-EP881014HU-B |
Recombinant Human Netrin-4 (NTN4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP881014HU1 | Recombinant Human Netrin-4 (NTN4), partial | E.coli |
CSB-MP881014HU2 | Recombinant Human Netrin-4 (NTN4), partial | Mammalian cell |
NTN4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E11900h | Human Netrin-4,Ntn4 ELISA Kit | serum, plasma, tissue homogenates | 1.95 ng/ml |