PDX1

PDX1, a transcription factor of the homeobox family, is vital for the development of the pancreas and the preservation of beta cell function. This factor exerts its influence by binding to the insulin gene promoter, modulating insulin synthesis in collaboration with other elements. Central to the maturation, differentiation of beta cells, and the regulation of insulin production and release, PDX1 is pivotal in pancreatic development and insulin regulation. As focus in diseases such as pancreatic hypoplasia and diabetes research, PDX1 holds promise for therapeutic and prognostic advancements in managing these conditions