PGK1

PGK1, phosphoglycerate kinase 1, is a key enzyme in the glycolytic pathway, found across a spectrum of organisms, from humans to animals and microorganisms. PGK1's principal mechanism of action involves catalyzing the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, generating ATP to fuel cells. This enzyme plays an integral role in energy metabolism, redox balance, and DNA repair. Beyond its glycolytic role, PGK1 also engages in non-glycolytic functions, such as aiding DNA replication as a cofactor for polymerase α and modulating cell proliferation, invasion, and metastasis in cancer cells through post-translational modifications. These diverse functions render PGK1 significant in cell biology and medical research, marking it as a key molecule for exploring disease mechanisms and potential therapeutic targets.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PGK1 Antibody (CSB-PA905158)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA905158(PGK1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA905158(PGK1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A549 cells, mouse liver tissue, hepG2 cells, Primary antibody: CSB-PA905158(PGK1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

Human phosphoglycerate kinase 1 (PGK1) ELISA kit (CSB-E17849h)

Validated Data

Code: CSB-E17849h

Size: 96T,5×96T,10×96T

Sensitivity: 7 pg/mL

Detection Range: 28 pg/mL-1800 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PGK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PGK1 Antibodies

PGK1 Proteins

PGK1 ELISA Kits

PGK1 Antibodies

PGK1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA00035B0Rb	PGK1 Antibody, HRP conjugated	Human	ELISA
CSB-PA00035C0Rb	PGK1 Antibody, FITC conjugated	Human
CSB-PA00035D0Rb	PGK1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA00035A0Rb	PGK1 Antibody	Human	ELISA, WB
CSB-PA017856GA01HU	PGK1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA905158	PGK1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA547426	PGK1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC

PGK1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA885315XA01DOA	PGK1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

PGK1 Antibodies for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Species Reactivity	Application
CSB-PA765629XA01DOT	PGK1 Antibody	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	ELISA, WB (ensure identification of antigen)

PGK1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA365449XA01SVG	PGK1 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

PGK1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA526437XA01SXV	pgk1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

PGK1 Proteins

PGK1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP017856RA CSB-EP017856RA CSB-BP017856RA CSB-MP017856RA CSB-EP017856RA-B	Recombinant Rat Phosphoglycerate kinase 1 (Pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP017856HU CSB-BP017856HU CSB-MP017856HU CSB-EP017856HU-B	Recombinant Human Phosphoglycerate kinase 1 (PGK1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP017856HU1	Recombinant Human Phosphoglycerate kinase 1 (PGK1), partial	E.coli
CSB-EP017856HU	Recombinant Human Phosphoglycerate kinase 1(PGK1)	E.coli

PGK1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP017856MO CSB-EP017856MO CSB-BP017856MO CSB-MP017856MO CSB-EP017856MO-B	Recombinant Mouse Phosphoglycerate kinase 1 (Pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP017856HO CSB-EP017856HO CSB-BP017856HO CSB-MP017856HO CSB-EP017856HO-B	Recombinant Horse Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP017856EQV CSB-EP017856EQV CSB-BP017856EQV CSB-MP017856EQV CSB-EP017856EQV-B	Recombinant Pan troglodytes Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Macropus eugenii (Tammar wallaby) (Notamacropus eugenii)

Code	Product Name	Source
CSB-YP017856MPE CSB-EP017856MPE CSB-BP017856MPE CSB-MP017856MPE CSB-EP017856MPE-B	Recombinant Macropus eugenii Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Rhizopus niveus

Code	Product Name	Source
CSB-YP017856RDC CSB-EP017856RDC CSB-BP017856RDC CSB-MP017856RDC CSB-EP017856RDC-B	Recombinant Rhizopus niveus Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-EP017856DXU CSB-BP017856DXU CSB-MP017856DXU CSB-EP017856DXU-B	Recombinant Cricetulus griseus Phosphoglycerate kinase 1 (PGK1)	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP017856DXU	Recombinant Cricetulus griseus Phosphoglycerate kinase 1 (PGK1)	Yeast

PGK1 Proteins for Hypocrea jecorina (Trichoderma reesei)

Code	Product Name	Source
CSB-YP321216HYE CSB-EP321216HYE CSB-BP321216HYE CSB-MP321216HYE CSB-EP321216HYE-B	Recombinant Hypocrea jecorina Phosphoglycerate kinase (pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)

Code	Product Name	Source
CSB-YP328900YAP CSB-EP328900YAP CSB-BP328900YAP CSB-MP328900YAP CSB-EP328900YAP-B	Recombinant Yarrowia lipolytica Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Candida maltosa (Yeast)

Code	Product Name	Source
CSB-YP334892CZJ CSB-EP334892CZJ CSB-BP334892CZJ CSB-MP334892CZJ CSB-EP334892CZJ-B	Recombinant Candida maltosa Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Hypocrea rufa (Trichoderma viride)

Code	Product Name	Source
CSB-YP335056THZ CSB-EP335056THZ CSB-BP335056THZ CSB-MP335056THZ CSB-EP335056THZ-B	Recombinant Trichoderma viride Phosphoglycerate kinase (pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Code	Product Name	Source
CSB-YP342394CZD CSB-EP342394CZD CSB-BP342394CZD CSB-MP342394CZD CSB-EP342394CZD-B	Recombinant Candida albicans Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP365449SVG CSB-EP365449SVG CSB-BP365449SVG CSB-MP365449SVG CSB-EP365449SVG-B	Recombinant Saccharomyces cerevisiae Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP526437SXV CSB-EP526437SXV CSB-BP526437SXV CSB-MP526437SXV CSB-EP526437SXV-B	Recombinant Schizosaccharomyces pombe Phosphoglycerate kinase (pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP017856MOV CSB-EP017856MOV CSB-BP017856MOV CSB-MP017856MOV CSB-EP017856MOV-B	Recombinant Macaca fascicularis Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP017856PI CSB-EP017856PI CSB-BP017856PI CSB-MP017856PI CSB-EP017856PI-B	Recombinant Pig Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

Code	Product Name	Source
CSB-YP017856MFB CSB-EP017856MFB CSB-BP017856MFB CSB-MP017856MFB CSB-EP017856MFB-B	Recombinant Methanosarcina acetivorans Phosphoglycerate kinase 1 (pgk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP017856BO CSB-EP017856BO CSB-BP017856BO CSB-MP017856BO CSB-EP017856BO-B	Recombinant Bovine Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP017856PYX CSB-EP017856PYX CSB-BP017856PYX CSB-MP017856PYX CSB-EP017856PYX-B	Recombinant Pongo abelii Phosphoglycerate kinase 1 (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)

Code	Product Name	Source
CSB-YP728177DIS CSB-EP728177DIS CSB-BP728177DIS CSB-MP728177DIS CSB-EP728177DIS-B	Recombinant Debaryomyces hansenii Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

Code	Product Name	Source
CSB-YP739437CZI CSB-EP739437CZI CSB-BP739437CZI CSB-MP739437CZI CSB-EP739437CZI-B	Recombinant Candida glabrata Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Source
CSB-YP765629DOT CSB-EP765629DOT CSB-BP765629DOT CSB-MP765629DOT CSB-EP765629DOT-B	Recombinant Ashbya gossypii Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Komagataella pastoris (Yeast) (Pichia pastoris)

Code	Product Name	Source
CSB-YP772042EVS CSB-EP772042EVS CSB-BP772042EVS CSB-MP772042EVS CSB-EP772042EVS-B	Recombinant Pichia pastoris Phosphoglycerate kinase (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP885315DOA CSB-EP885315DOA CSB-BP885315DOA CSB-MP885315DOA CSB-EP885315DOA-B	Recombinant Arabidopsis thaliana Phosphoglycerate kinase 1, chloroplastic (PGK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PGK1 ELISA Kit

PGK1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E17849h	Human phosphoglycerate kinase 1 (PGK1) ELISA kit	serum, plasma, tissue homogenates, cell lysates	7 pg/mL

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PGK1

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