The progranulin (PGRN) is a secretory glycoprotein composed of multiple tandemly repeated structural domains, capable of hydrolyzing into various granulin peptides. It exhibits broad specificity in cells and tissues, exerting diverse functions through binding with multiple receptors, such as regulating immune cell function and promoting neural regeneration. In neurons, PGRN is secreted in an activity-dependent manner, influencing synaptic structure and function. Although the signaling pathway mechanism of PGRN is not fully understood, it is known to play a crucial role in immune responses and neural system functions, and may be associated with familial neurodegenerative diseases.
Human Granulins(GRN) ELISA kit
Validated Data
Code:CSB-EL009939HU
Size:96T/48T
Sensitivity:1.95 pg/mL
Detection Range:7.8 pg/mL-500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following PGRN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PGRN Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009939GA01HU | GRN Antibody |
Human | ELISA,WB,IHC |
CSB-PA009939ESR2HU | GRN Antibody |
Human | ELISA, IHC |
PGRN Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP009939HU CSB-EP009939HU CSB-BP009939HU CSB-MP009939HU CSB-EP009939HU-B |
Recombinant Human Granulins (GRN) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PGRN ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL009939HU | Human Granulins(GRN) ELISA kit |
serum, plasma, cell culture supernates | 1.95 pg/mL |