PIAS3

PIAS3, full name protein inhibitor of activated STAT3. It is an intracellular signaling regulatory protein inhibiting STAT3 pathway, regulating cell proliferation, apoptosis and immune balance. PIAS3 deficiency causes excessive STAT3 activation, promoting tumor proliferation and immune suppression. Its dysregulation also correlates with autoimmune diseases. PIAS3 activators are under preclinical research.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PIAS3 Antibody (CSB-PA896765DSR1HU)

Validated Data

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA896765DSR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA896765DSR1HU at dilution of 1:100

The following PIAS3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PIAS3 Antibodies

PIAS3 Proteins

PIAS3 Antibodies

PIAS3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA017959GA01HU	PIAS3 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA896765DSR1HU	PIAS3 Antibody	Human	ELISA, IHC
CSB-PA283252	PIAS3 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA003780	PIAS3 Antibody	Human,Mouse,Rat	WB, IHC, ELISA

PIAS3 Proteins

PIAS3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP017959MO CSB-EP017959MO CSB-BP017959MO CSB-MP017959MO CSB-EP017959MO-B	Recombinant Mouse E3 SUMO-protein ligase PIAS3 (Pias3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PIAS3 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP017959RA CSB-EP017959RA CSB-BP017959RA CSB-MP017959RA CSB-EP017959RA-B	Recombinant Rat E3 SUMO-protein ligase PIAS3 (Pias3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PIAS3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP896765HU CSB-EP896765HU CSB-BP896765HU CSB-MP896765HU CSB-EP896765HU-B	Recombinant Human E3 SUMO-protein ligase PIAS3 (PIAS3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP896765HU1	Recombinant Human E3 SUMO-protein ligase PIAS3 (PIAS3), partial	E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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PIAS3

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