PIP5K1A encodes Phosphatidylinositol - 4 - phosphate 5 - kinase type - 1 alpha. It is also known as PIPKI - alpha. This protein plays a key role in lipid metabolism by catalyzing the synthesis of phosphatidylinositol 4,5 - bisphosphate (PIP2) from phosphatidylinositol 4 - phosphate. PIP5K1A is involved in the PI3K - AKT and Rho signaling pathways.
Mutations or abnormal expression of PIP5K1A are associated with some cancers and neurological disorders. In drug development, PIP5K1A is considered a potential target. Some small - molecule inhibitors are under pre - clinical research to explore their efficacy in treating related diseases.
Validated Data
Western blot analysis of extracts from 3T3 cells, using TUT1 antiobdy.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TUT1 antibody.
The following PIP5K1A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PIP5K1A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018025GA01HU | PIP5K1A Antibody | Human,Mouse,Rat | ELISA,WB,IF,IP |
CSB-PA046708 | TUT1 Antibody | Human | ELISA,WB,IHC |
CSB-PA050066 | TUT1 Antibody | Human | WB, IHC, ELISA |
CSB-PA960186 | PIP5K1A Antibody | Human | ELISA,WB,IHC |
CSB-PA094535 | PIP5K1A Antibody | Human | ELISA,WB,IHC |
CSB-PA859110ESR1HU | PIP5K1A Antibody | Human, Mouse | ELISA, WB, IHC |
PIP5K1A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP018025MO CSB-EP018025MO CSB-BP018025MO CSB-MP018025MO CSB-EP018025MO-B |
Recombinant Mouse Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (Pip5k1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIP5K1A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP859110HU CSB-EP859110HU CSB-BP859110HU CSB-MP859110HU CSB-EP859110HU-B |
Recombinant Human Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP884477HU CSB-EP884477HU CSB-BP884477HU CSB-MP884477HU CSB-EP884477HU-B |
Recombinant Human Speckle targeted PIP5K1A-regulated poly (A) polymerase (TUT1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |