PNLIP

PNLIP encodes pancreatic lipase, also known as steapsin. This protein is crucial for lipid digestion. It acts by hydrolyzing triglycerides into fatty acids and glycerol in the small intestine. The process is part of the lipid metabolic pathway.
Mutations in PNLIP can lead to lipid - malabsorption syndromes, such as steatorrhea. In terms of drug development, some research is exploring compounds that can modulate its activity to treat obesity and related metabolic disorders, aiming to either enhance or inhibit its function based on the therapeutic goal.