POT1 Research Reagents

Protection of telomeres protein 1 is a protein in humans that is encoded by POT1 gene. Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA-binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

The following POT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

POT1 Antibodies

POT1 Antibodies for Homo sapiens (Human)

POT1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

POT1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

POT1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

POT1 Proteins

POT1 Proteins for Gallus gallus (Chicken)

POT1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

POT1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

POT1 Proteins for Mus musculus (Mouse)

POT1 Proteins for Homo sapiens (Human)

POT1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

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