Rho-related GTP-binding protein RhoH is a protein in humans that is encoded by RHOH gene. Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection. Plays critical roles in mast cell function by facilitating phosphorylation of SYK in Fc epsilon RI-mediated signal transduction. Essential for the phosphorylation of LAT, LCP2, PLCG1 and PLCG2 and for Ca(2+) mobilization in mast cells (By similarity).
The following RHOH reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
RHOH Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009834 | RHOH Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA618992LA01HU | RHOH Antibody |
Human | ELISA, IHC, IF |
CSB-PA618992LB01HU | RHOH Antibody, HRP conjugated |
Human | ELISA |
CSB-PA618992LC01HU | RHOH Antibody, FITC conjugated |
Human | |
CSB-PA618992LD01HU | RHOH Antibody, Biotin conjugated |
Human | ELISA |
RHOH Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618992HU CSB-EP618992HU CSB-BP618992HU CSB-MP618992HU CSB-EP618992HU-B |
Recombinant Human Rho-related GTP-binding protein RhoH (RHOH) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RHOH Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP641321BO CSB-EP641321BO CSB-BP641321BO CSB-MP641321BO CSB-EP641321BO-B |
Recombinant Bovine Rho-related GTP-binding protein RhoH (RHOH) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RHOH Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP861532MO CSB-EP861532MO CSB-BP861532MO CSB-MP861532MO CSB-EP861532MO-B |
Recombinant Mouse Rho-related GTP-binding protein RhoH (Rhoh) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |