RNLS

RNLS, also known as Renalase, is a flavoprotein secreted by the kidney. It has several common aliases, such as FLJ20376 and C10orf55. Renalase exerts its effects by binding to and activating specific adrenergic receptors, thereby modulating sympathetic nervous system activity. It is involved in the regulation of blood pressure and cardiac function through the adrenergic signaling pathway.
Renalase is associated with various diseases, including hypertension and heart failure. In recent years, research on renalase-targeted drugs has advanced. Scientists are exploring drugs that can enhance renalase activity or mimic its functions to develop new treatments for cardiovascular - related diseases, showing promising potential for future clinical applications.