Rho-associated protein kinase 2 is a protein in humans that is encoded by ROCK2 gene. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication.
The following ROCK2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ROCK2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020059GA01HU | ROCK2 Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA035451 | Phospho-ROCK2 (Tyr722) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA020059ESR1HU | ROCK2 Antibody |
Human, Rat | ELISA, WB, IHC, IF |
CSB-PA004018 | ROCK2 Antibody |
Human,Mouse,Rat,Monkey | WB, ELISA |
CSB-PA005112 | ROCK2 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA242246 | ROCK2 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA081497 | ROCK2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA020059DA01HU | ROCK2 Antibody |
Human, Mouse | ELISA, WB |
CSB-PA020059DB01HU | ROCK2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA020059DC01HU | ROCK2 Antibody, FITC conjugated |
Human | |
CSB-PA020059DD01HU | ROCK2 Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA152329A0HU | ROCK2 Recombinant Monoclonal Antibody |
Human, Mouse, Rat | ELISA, WB, IF |
ROCK2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP020059MO CSB-EP020059MO CSB-BP020059MO CSB-MP020059MO CSB-EP020059MO-B |
Recombinant Mouse Rho-associated protein kinase 2 (Rock2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP020059HU CSB-EP020059HU CSB-BP020059HU CSB-MP020059HU CSB-EP020059HU-B |
Recombinant Human Rho-associated protein kinase 2 (ROCK2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP636705BO CSB-EP636705BO CSB-BP636705BO CSB-MP636705BO CSB-EP636705BO-B |
Recombinant Bovine Rho-associated protein kinase 2 (ROCK2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP720322RA CSB-EP720322RA CSB-BP720322RA CSB-MP720322RA CSB-EP720322RA-B |
Recombinant Rat Rho-associated protein kinase 2 (Rock2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E14993h | Human Rho-associated coiled-coil containing protein kinase 2(Rock-2) ELISA Kit |
serum, plasma, cell culture supernates | 7.8 pg/mL |