S100P is a member of the S100 family of calcium-binding proteins, also known as S100 protein P. It plays important roles in regulating cell proliferation, differentiation, apoptosis, and motility by interacting with target proteins in a calcium-dependent manner. S100P is involved in multiple signaling pathways, such as the MAPK and PI3K-Akt pathways, which are crucial for cell survival and growth.
Altered expression of S100P has been associated with various diseases, especially cancers like pancreatic, breast, and prostate cancer. It serves as a potential biomarker and therapeutic target. Currently, several drug discovery efforts are underway to develop S100P inhibitors to block its function, aiming to provide new treatment options for related diseases.
Recombinant Human Protein S100-P (S100P) (CSB-EP020645HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
S100P Antibody (CSB-PA020645LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA020645LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA020645LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human S100 calcium binding protein P(S100P) ELISA Kit (CSB-E14080h)
Validated Data
Code: CSB-E14080h
Size: 96T,5×96T,10×96T
Sensitivity: 19.5 pg/mL
Detection Range: 78 pg/mL-5000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following S100P reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
S100P Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020645GA01HU | S100P Antibody | Human | ELISA,WB,IHC |
CSB-PA040287 | S100P Antibody | Human | WB, IHC, ELISA |
CSB-PA825365 | S100P Antibody | Human | ELISA,WB |
CSB-PA031961 | S100P Antibody | Human | ELISA,WB |
CSB-PA020645LA01HU | S100P Antibody | Human | ELISA, IHC, IF |
CSB-PA020645LB01HU | S100P Antibody, HRP conjugated | Human | ELISA |
CSB-PA020645LC01HU | S100P Antibody, FITC conjugated | Human | |
CSB-PA020645LD01HU | S100P Antibody, Biotin conjugated | Human | ELISA |
S100P Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP020645HU CSB-BP020645HU CSB-MP020645HU CSB-EP020645HU-B |
Recombinant Human Protein S100-P (S100P) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP020645HU | Recombinant Human Protein S100-P (S100P) | E.coli |
S100P ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E14080h | Human S100 calcium binding protein P(S100P) ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/mL |