SEPTIN4, also known as Septin 4, is a protein coding gene that plays a crucial role in cytoskeletal organization and cell division. It is a member of the septin family, which is highly conserved across various organisms. SEPTIN4 is involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development. Common aliases for SEPTIN4 include H5, ARTS, MART, SEP4, CE5B3, SEPT4, PNUTL2, hucep-7, BRADEION, C17orf47, and Septin-4. The protein functions by regulating the assembly and disassembly of actin filaments, which is essential for various cellular processes. SEPTIN4 is implicated in several signaling pathways, including those related to cell cycle control, cell division, and apoptosis. Its dysregulation is associated with various diseases, such as male infertility, liver cancer, and colorectal cancer. Research on SEPTIN4 has led to potential therapeutic targets for drug development, particularly in the context of cancer treatment.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA270601(SEPT4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA270601(SEPT4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following SEPTIN4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SEPTIN4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA270601 | SEPT4 Antibody | Human | ELISA,IHC |
CSB-PA113302 | SEPT4 Antibody | Human | ELISA,IHC |
SEPTIN4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP021027HU CSB-EP021027HU CSB-BP021027HU CSB-MP021027HU CSB-EP021027HU-B |
Recombinant Human Septin-4 (SEPTIN4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |