SH3 and multiple ankyrin repeat domains protein 3 is a protein in humans that is encoded by SHANK3 gene. Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters.
The following SHANK3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SHANK3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
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CSB-YP674485MO CSB-EP674485MO CSB-BP674485MO CSB-MP674485MO CSB-EP674485MO-B |
Recombinant Mouse SH3 and multiple ankyrin repeat domains protein 3 (Shank3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SHANK3 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
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CSB-YP872887RA CSB-EP872887RA CSB-BP872887RA CSB-MP872887RA CSB-EP872887RA-B |
Recombinant Rat SH3 and multiple ankyrin repeat domains protein 3 (Shank3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SHANK3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
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CSB-YP880134HU CSB-EP880134HU CSB-BP880134HU CSB-MP880134HU CSB-EP880134HU-B |
Recombinant Human SH3 and multiple ankyrin repeat domains protein 3 (SHANK3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |