SIKE1

SIKE1, also known as suppressor of IKBKE 1, is a protein coding gene that interacts with IKK-epsilon and TBK1, acting as a suppressor of TLR3 and virus-triggered interferon activation pathways. It plays a crucial role in regulating the immune response to infections. SIKE1 is associated with various diseases, including Noonan Syndrome 6 and Cerebral Cavernous Malformations. Recent research has focused on the potential of targeting SIKE1 for drug development, exploring its role in immune regulation and its implications in disease progression.