SLC13A5 encodes the sodium-coupled citrate transporter 2 (NaCT2), also known as NaDC3. This protein plays a crucial role in cellular metabolism by transporting citrate across the cell membrane. It functions as an electrogenic sodium/citrate symporter. The SLC13A5 is involved in the tricarboxylic acid (TCA) cycle and fatty acid synthesis pathways.
Mutations in the SLC13A5 gene have been linked to early infantile epileptic encephalopathy - 39 (EIEE39), a severe neurological disorder. Currently, research on drugs targeting SLC13A5 is in progress, aiming to develop therapies for EIEE39 and related metabolic diseases.
SLC13A5 Antibody (CSB-PA768239LA01HU)
Validated Data
Western Blot
Positive WB detected in: HepG2 whole cell lysate(30µg), Raji whole cell lysate(30µg), JK whole cell lysate(30µg), LO2 whole cell lysate(30µg), HT29 whole cell lysate(30µg), 293 whole cell lysate(30µg),Mouse Liver tissue lysate(30µg),Rat Liver tissue lysate(30µg)
All lanes: SLC13A5 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 64,59,62 kDa
Observed band size: 64 kDa
Exposure time: 120s
IHC image of CSB-PA768239LA01HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody.
The following SLC13A5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SLC13A5 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA768239LA01HU | SLC13A5 Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA768239LB01HU | SLC13A5 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA768239LC01HU | SLC13A5 Antibody, FITC conjugated | Human | |
| CSB-PA768239LD01HU | SLC13A5 Antibody, Biotin conjugated | Human | ELISA |
SLC13A5 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP768239HU CSB-EP768239HU CSB-BP768239HU CSB-MP768239HU CSB-EP768239HU-B |
Recombinant Human Solute carrier family 13 member 5 (SLC13A5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |