SLC1A4

SLC1A4 encodes the solute carrier family 1 member 4 protein, commonly known as ASCT1. It is an important membrane - associated transporter. ASCT1 mediates the sodium - dependent transport of neutral amino acids across the cell membrane. It is involved in the excitatory amino acid signaling pathway, playing a role in maintaining cellular amino acid homeostasis.
Dysregulation of SLC1A4 is linked to several neurological disorders, such as epilepsy. In drug development, researchers are exploring potential drugs that can modulate ASCT1 activity. These drugs aim to correct amino acid transport imbalances, with the hope of providing new treatment options for related diseases.