SLC2A10

The gene SLC2A10 encodes the protein GLUT10, also known as solute carrier family 2 member 10. This protein functions as a glucose transporter, facilitating the uptake of glucose into cells. It operates through the sodium-glucose co-transporter mechanism, which is crucial for maintaining glucose homeostasis. GLUT10 is involved in various signaling pathways, including insulin signaling, and is associated with diseases such as type 2 diabetes, where it contributes to increased risk of peripheral artery disease. Recent advancements in drug research aim to modulate GLUT10 activity for therapeutic purposes.