SLC44A4

SLC44A4, a type of transmembrane protein, is part of a larger group called the solute carrier family 44. SLC44A4 protein is notably present in tissues such as the colon and stomach, where it facilitates sodium-dependent transmembrane transport, potentially playing a role in choline uptake, which is vital for the function of cholinergic neurons. SLC44A4 contributes to cell membrane synthesis and significantly impacts cell growth and differentiation. The abnormal expression of SLC44A4 is associated with various diseases, including sialic acid storage disease (a lysosomal storage disease), hearing loss, prostate cancer, etc, further underscoring SLC44A4's role as a potential therapeutic target and biomarker in these diseases.