SMARCA4, also known as BRG1 or hBRM, is a multifaceted protein encoded by the SMARCA4 gene and a central component of the SWI/SNF chromatin remodeling complex. It modulates chromatin structure, facilitates transcription factor DNA binding, and influences gene expression through its ATPase activity. SMARCA4 is pivotal in cell proliferation, differentiation, and development, and is intimately connected to tumorigenesis. Defective SMARCA4 function can result in genetic disorders and cancer, highlighting its potential as a target for pharmaceutical development and therapeutic intervention.
Recombinant Human Transcription activator BRG1 (SMARCA4), partial (CSB-EP021801HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SMARCA4 Antibody (CSB-PA021801LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA021801LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA021801LA01HU at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Transcription activator BRG1(SMARCA4) ELISA kit (CSB-EL021801HU)
Validated Data
Code: CSB-EL021801HU
Size: 96T,5×96T,10×96T
Sensitivity: 6.25 pg/mL
Detection Range: 25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following SMARCA4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SMARCA4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021801KA01HU | SMARCA4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA021801GA01HU | SMARCA4 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA238794 | SMARCA4 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA050103 | SMARCA4 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA843993 | SMARCA4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA595142 | SMARCA4 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA021801LA01HU | SMARCA4 Antibody | Human | ELISA, IHC, IF |
CSB-PA021801LC01HU | SMARCA4 Antibody, FITC conjugated | Human | |
CSB-PA021801LD01HU | SMARCA4 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA090878A0HU | SMARCA4 Recombinant Monoclonal Antibody | Human | ELISA, IHC, IF, FC |
SMARCA4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP021801HU | Recombinant Human Transcription activator BRG1 (SMARCA4), partial | Yeast |
CSB-EP021801HU1 | Recombinant Human Transcription activator BRG1 (SMARCA4), partial | E.coli |
CSB-BP021801HU CSB-MP021801HU |
Recombinant Human Transcription activator BRG1 (SMARCA4), partial | Baculovirus Mammalian cell |
CSB-EP021801HU | Recombinant Human Transcription activator BRG1 (SMARCA4), partial | E.coli |
CSB-EP021801HU-B | Recombinant Human Transcription activator BRG1 (SMARCA4), partial,Biotinylated | E.coli |
SMARCA4 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP021801BO CSB-EP021801BO CSB-BP021801BO CSB-MP021801BO CSB-EP021801BO-B |
Recombinant Bovine Transcription activator BRG1 (SMARCA4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMARCA4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP659697MO CSB-EP659697MO CSB-BP659697MO CSB-MP659697MO CSB-EP659697MO-B |
Recombinant Mouse Transcription activator BRG1 (Smarca4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMARCA4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP811687RA CSB-EP811687RA CSB-BP811687RA CSB-MP811687RA CSB-EP811687RA-B |
Recombinant Rat Transcription activator BRG1 (Smarca4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMARCA4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL021801HU | Human Transcription activator BRG1(SMARCA4) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |