SORT1

SORT1, or sorting protein 1, alias Sortilin, NT3, Gp95, NTR3, LDLCQ6, is a transmembrane protein belonging to the VPS10-related sortilin protein family.
SORT1 functions in multiple subcellular regions, including the Golgi, endosomes, endoplasmic reticulum, and cell membranes, and its main function is to act as a sorting receptor involved in protein transport and metabolism. SORT1 can transport proteins from the Golgi to lysosomes and endosomes through various pathways and has been associated with the internalization and translocation of a variety of proteins.
SORT1 expression levels may affect the risk of myocardial infarction and has been associated with a variety of diseases, including lipid metabolism disorders, certain types of cancer, and neurodegenerative diseases. SORT1 is biologically important in regulating cholesterol metabolism, promoting neuronal apoptosis, and possibly influencing insulin response.

Popular Product:

SORT1 Antibody (CSB-PA859102LA01HU)

Validated Data

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Sortilin(SORT1) ELISA kit (CSB-EL022412HU)

Validated Data

Code: CSB-EL022412HU

Size: 96T,5×96T,10×96T

Sensitivity: 11.72 pg/mL

Detection Range: 46.88 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following SORT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SORT1 Antibodies

SORT1 Proteins

SORT1 ELISA Kits

SORT1 Antibodies

SORT1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA022412GA01HU	SORT1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA448728	SORT1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA194090	SORT1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA859102LA01HU	SORT1 Antibody	Human	ELISA, IHC
CSB-PA859102LB01HU	SORT1 Antibody, HRP conjugated	Human	ELISA
CSB-PA859102LC01HU	SORT1 Antibody, FITC conjugated	Human
CSB-PA859102LD01HU	SORT1 Antibody, Biotin conjugated	Human	ELISA

SORT1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA022412LA01RA	Sort1 Antibody	Rat	ELISA
CSB-PA022412LB01RA	Sort1 Antibody, HRP conjugated	Rat	ELISA

SORT1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA761235XA01DIL	sort1 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

SORT1 Proteins

SORT1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-EP022412RA	Recombinant Rat Sortilin (Sort1), partial	E.coli
CSB-YP022412RA	Recombinant Rat Sortilin (Sort1), partial	Yeast
CSB-BP022412RA CSB-MP022412RA CSB-EP022412RA-B	Recombinant Rat Sortilin (Sort1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP022412RAa0	Recombinant Rat Sortilin (Sort1), partial	E.coli

SORT1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP740787MO CSB-EP740787MO CSB-BP740787MO CSB-MP740787MO CSB-EP740787MO-B	Recombinant Mouse Sortilin (Sort1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SORT1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP761235DIL CSB-EP761235DIL CSB-BP761235DIL CSB-MP761235DIL CSB-EP761235DIL-B	Recombinant Danio rerio Sortilin (sort1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SORT1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP859102HU CSB-EP859102HU CSB-BP859102HU CSB-MP859102HU CSB-EP859102HU-B	Recombinant Human Sortilin (SORT1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SORT1 ELISA Kit

SORT1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL022412HU	Human Sortilin(SORT1) ELISA kit	serum, plasma, tissue homogenates, cell lysates	11.72 pg/mL

SORT1 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL022412MO	Mouse Sortilin(SORT1) ELISA kit	serum, plasma, tissue homogenates	1.56 pg/mL

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