Sortilin is a protein in humans that is encoded by SORT1 gene. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs).
The following SORT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SORT1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022412GA01HU | SORT1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA448728 | SORT1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA194090 | SORT1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA859102LA01HU | SORT1 Antibody |
Human | ELISA, IHC |
CSB-PA859102LB01HU | SORT1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA859102LC01HU | SORT1 Antibody, FITC conjugated |
Human | |
CSB-PA859102LD01HU | SORT1 Antibody, Biotin conjugated |
Human | ELISA |
SORT1 Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022412LA01RA | Sort1 Antibody |
Rat | ELISA |
CSB-PA022412LB01RA | Sort1 Antibody, HRP conjugated |
Rat | ELISA |
SORT1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA761235XA01DIL | sort1 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
SORT1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-EP022412RA | Recombinant Rat Sortilin (Sort1), partial |
E.coli |
CSB-YP022412RA | Recombinant Rat Sortilin (Sort1), partial |
Yeast |
CSB-BP022412RA CSB-MP022412RA CSB-EP022412RA-B |
Recombinant Rat Sortilin (Sort1) |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP022412RAa0 | Recombinant Rat Sortilin (Sort1), partial |
E.coli |
SORT1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP740787MO CSB-EP740787MO CSB-BP740787MO CSB-MP740787MO CSB-EP740787MO-B |
Recombinant Mouse Sortilin (Sort1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SORT1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP761235DIL CSB-EP761235DIL CSB-BP761235DIL CSB-MP761235DIL CSB-EP761235DIL-B |
Recombinant Danio rerio Sortilin (sort1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SORT1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP859102HU CSB-EP859102HU CSB-BP859102HU CSB-MP859102HU CSB-EP859102HU-B |
Recombinant Human Sortilin (SORT1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SORT1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL022412HU | Human Sortilin(SORT1) ELISA kit |
serum, plasma, tissue homogenates, cell lysates | 11.72 pg/mL |
SORT1 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL022412MO | Mouse Sortilin(SORT1) ELISA kit |
serum, plasma, tissue homogenates | 1.56 pg/mL |