SOS1

SOS1, a guanine nucleotide exchange factor (GEF) essential for cell signaling, is also referred to by several names, including non-seven-kinase homologue 1, GF1, HGF, NS4, and GGF1. This protein is found across a broad range of organisms, from plants to mammals, and is essential for activating Ras, a protein that governs key cellular processes such as proliferation, differentiation, and various biological functions. In plants, SOS1 is particularly important for salt tolerance, as it helps manage salt stress by facilitating sodium ion transport. By serving as a pivotal component in both cell signal transduction and the response to environmental stress, SOS1 helps organisms maintain homeostasis and adapt to fluctuating conditions. Its critical function in both plant and animal systems highlights its potential as a target for therapeutic strategies aimed at enhancing stress resilience and regulating growth pathways.