SOS1, a guanine nucleotide exchange factor (GEF) essential for cell signaling, is also referred to by several names, including non-seven-kinase homologue 1, GF1, HGF, NS4, and GGF1. This protein is found across a broad range of organisms, from plants to mammals, and is essential for activating Ras, a protein that governs key cellular processes such as proliferation, differentiation, and various biological functions. In plants, SOS1 is particularly important for salt tolerance, as it helps manage salt stress by facilitating sodium ion transport. By serving as a pivotal component in both cell signal transduction and the response to environmental stress, SOS1 helps organisms maintain homeostasis and adapt to fluctuating conditions. Its critical function in both plant and animal systems highlights its potential as a target for therapeutic strategies aimed at enhancing stress resilience and regulating growth pathways.
SOS1 Recombinant Monoclonal Antibody (CSB-RA561936A0HU)
Validated Data
Overlay Peak curve showing Hela cells stained with CSB-RA561936A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
The following SOS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SOS1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022413GA01HU | SOS1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA022413XA01HU | SOS1 Antibody | Homo sapiens (Human) | ELISA, WB (ensure identification of antigen) |
CSB-PA726788LA01HU | SOS1 Antibody | Human, Rat | ELISA, WB, IHC, IF |
CSB-PA726788LB01HU | SOS1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA726788LC01HU | SOS1 Antibody, FITC conjugated | Human | |
CSB-PA726788LD01HU | SOS1 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA561936A0HU | SOS1 Recombinant Monoclonal Antibody | Human | ELISA, FC |
SOS1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP726788MO CSB-EP726788MO CSB-BP726788MO CSB-MP726788MO CSB-EP726788MO-B |
Recombinant Mouse Son of sevenless homolog 1 (Sos1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |