TET2, part of the TET protein family that includes TET1, TET2, and TET3, is an enzyme that converts 5-methylcytosine to 5-hydroxymethylcytosine, initiating a demethylation process crucial for DNA modification. TET2 enzyme plays a significant role in determining cell fate, differentiation, tumor development, and immune regulation. Abnormalities in TET2 expression or function are linked to a variety of diseases, such as myeloid neoplasms and immune-related disorders. TET2 influences cell proliferation and differentiation by regulating gene expression and DNA methylation, contributing to tumor suppression. Additionally, TET2 impacts the secretion of inflammatory factors and is involved in the modulation of inflammatory responses within the immune system.
TET2 Antibody (CSB-PA764560ESR1HU)
Validated Data
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA764560ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA764560ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA764560ESR1HU at dilution of 1:100
The following TET2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TET2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA023397GA01HU | TET2 Antibody | Human | ELISA,WB |
CSB-PA764560ESR1HU | TET2 Antibody | Human | ELISA, IHC |
TET2 Antibodies for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA212085XA01DOA | TET2 Antibody | Arabidopsis thaliana | ELISA, WB (ensure identification of antigen) |
TET2 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA678395ZA01MO | Tet2 Antibody | Mus musculus | ELISA, WB (ensure identification of antigen) |
TET2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP678395MO CSB-BP678395MO CSB-MP678395MO CSB-EP678395MO-B |
Recombinant Mouse Methylcytosine dioxygenase TET2 (Tet2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP678395MO | Recombinant Mouse Methylcytosine dioxygenase TET2 (Tet2), partial | E.coli |
TET2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP764560HU CSB-EP764560HU CSB-BP764560HU CSB-MP764560HU CSB-EP764560HU-B |
Recombinant Human Methylcytosine dioxygenase TET2 (TET2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |